Neoantigen Targeted Therapy Development

[nickcooper]

Based on the advantages of tumor specificity and immunogenetics, neoantigens can become new targets for cancer immunotherapy, including tumor vaccines, ACTs, and antibody-based therapies. Neoantigens include individualized neoantigens for each patient or common neoantigens expressed across many patient cancers. Since personalized neoantigens are patient-specific, they cannot be used to target large numbers of patients. With recent advances in high-throughput sequencing, personalized neoantigens enable the immune system to target appropriate immunogenic epitopes of malignancies in the absence of predefined public antigens.

Learn more：neoantigen for cancer immunotherapy