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cataliesw



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re: Foot Pad Administration of Liposomes

Postby cataliesw on Tue Mar 19, 2024 2:02 am
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The foot pad administration of liposomes, specifically in rodents, involves the direct injection of liposomes into the plantar surface of the hind foot. Foot pad administration takes advantage of the unique physiology of the foot pad area. The foot pads are thick, hairless, and have a thinner skin layer compared to other body parts. This allows for a high degree of absorption and uptake of administered substances.



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By using this method, modified phages have been obtained at high frequencies (10 to 15%), thus enabling putative mutants to be screened by a small number of PCRs, without the requirement for further selection.
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